Forgot Your Password?
 
Create Your FREE Account
Would you like to Register using Facebook? You will get News and Announcements directly in your Facebook.
Register Without Facebook
E Learning

Expert Notes

  • Special Notes Prepared for GPAT/NIPER-JEE Exams.
  • Prepared Exclusively by GPATOnline Experts Team.
  • Detailed and Specific Solution.
  • Available Online and Printed Format
Online Test

Online Test

  • Pre configured test sets for GPAT 2013.
  • Get instant result.
  • Auto analyzer tool.
  • Unlimits tests.
E Learning

e Learning

  • Online learning solution - any time, any where.
  • Targeted on learning system.
  • Hints for complex questions.
  • View question and answer format.
Expert Advice

Expert Advice

  • Do you have any douts ?
  • Need assistance ?
  • Ask your questions to our experts.
  • A specialised team of industrial and academic experts.
Announcements | News | Alerts
  • Institute of Chemical Technology, ICT ADMISSIONS 2014-15 , Mumbai Institute of Chemical Technology, Matunga, Mumbai-19 announced admission 2014-15.Last date of M. Pharm application form: 19 April 2014.Last date of Ph D application form: 30 April 2014.For more details .... Read more

  • NIPER JEE 2014 National Institute of Pharmaceutical Education and Research (NIPER) announced online registration for NIPER JEE 2014 will open on 29th April 2014 to 12th May 2014. Entrance examination will held on 8th June 2014.NIPER PhD Joint admission test 2014 wil.... Read more

  • GPAT 2014 Qualification Cut-of -list Dear All,First of all Congratulations to all who qualify GPAT 2014.The most common quastion of GPAT 2014 qualifier - Shall I eligible to get stipend / scholarship for M. Pharm course ? Answer is here :.... Read more

Pharma Events & Conferences
Question of the Day
Concept of the Week

  • Physiological barrier to distribution of drugs

    1. Capillary endothelial barrier: All drugs (ionized, non-ionized) with molecular size less than 600 daltons diffuse through the capillary endothelium.

    2. Cell membrane barrier: Once a drug diffuses from the capillary wall into extracellualar fluid, its further entry into cells of most tissues is limited by its permeability through membrane (Similar to lipoidal barrier).

    3. Blood-brain barrier (BBB): Brain capillaries consist of endothelial cells which are joint together to one another by continuous tight intracellular junctions called as blood-brain barrier.
    Promotion of crossing BBB by :
    a) use of DMSO (permeation enhancer).
    b) Osmotic disruption of BBB by infusing internal carotid artery with mannitol.
    c) use of dihydropyridine redox system as drug carriers to the brain.

    4. Blood-CSF barrier: Cerebrospinal fluid (CSF) formed by choroid plexus of lateral, third and fourth ventricles. Choroid cells are joined together by tight junction forming blood-CSF barrier.

    5. Placental barrier: The maternal and fetal blood vessels are separated by number of tissue layers made of fetal trophoblast basement membrane and endothelium which together constitute the placental barrier.

    6. Blood-testis barrier: This barrier is located at the sertoli-sertoli cell junction. It is tight junction between neighboring sertoli cells that act as blood testis barrier.

     

Like us on Facebook
Pharma Events & Conferences