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  • Energetics in palmitic acid oxidation

    Energetics in palmitic acid oxidation:

    Mechanism ATP yield
    β-oxidation 7 cycles

    7 FADH2  –> 14 ATP (1 FADH2 = 2 ATP)

    7 NADH  –> 21 ATP (1 NADH= 3 ATP)

    14

    21

    From 8 acetyl CoA

    TCA cycle : Each acetyl CoA = 12 ATP

    96
    Total energy from one mole of palmitoyl CoA 131
    Energy utilized for activation -2
    Net  yield of oxidation 129

    The summary of β-oxidation of palmitoyl CoA is shown below:

    Palmitoyl CoA + 7 CoASH + 7 FAD + 7 NAD+ + 7H2O  —>

    8 Acetyl CoA + 7 FADH2 + 7 NADH + 7H+

    The energy yield by its oxidation – 129 ATP  (129 x 7.3 Cal) = 940 Cal

     

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